Below are the most important things to keep in mind when searching for the right domains.

1. Relevance
Make sure there is a clear connection between your domain name and your website. Domains that are too generic make this difficult. For example: PetsToys.com is better than PetsWeb.net.
2. Easy to Remember
Find domain names that are catchy, short, and easy to spell and say. Pronounce the domain three times aloud. Does it sound natural? Imagine yourself telling a potential customer about your website. Is it easy to convey and remember?
3. Evaluate Keyword Searches
If your domain name is an exact match of a search keyword, your website will likely appear near the top of those results. This can help your site get valuable traffic. Consider the most popular and relevant keyword searches for your business and see if they are available as domain names. You can try this by going to any search engine such as yahoo.com, google.com, or msn.com.
4. Pay Attention to the Extension
.com is the most popular. Others that are well-known and can deliver value are .net, .org, .biz, and .info. You must consider your competition and whether you want to buy all the extensions for your domain name. If you sell products to an international market, consider country-code domains. In this case, you might secure the .com, the .net, and the country-code, as appropriate (e.g., .co.uk).
5. Find Similar Domains
You may find a number of attractive domains for your business. You should consider protecting your brand and increasing your reach by securing multiple names. There could be multiple opportunities to get search engine traffic. You can easily forward one URL to another domain, which means that you can create one website that many domains point to.

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It is a nice post..........
I register my domain name, through this site http://www.thewebpole.com/twp/domain-name-search/
It has the best methods for domain name registration, bulk registration, domain name transfer and domain name Appraisals!!!

Royal thanks for your useful tip regarding domain name choosing. I generally choose keyword embedded domain name.